View a map with driving directions using your preferred map provider: Google Maps, Bing Maps, or MapQuest. You can use DriveDistance.com to get the full driving distance from Palatine to Cape Girardeau with directions.
The total driving distance from Palatine, IL to Cape Girardeau, MO is 396 miles or 637 kilometers.
Your trip begins in Palatine, Illinois. It ends in Cape Girardeau, Missouri.
If you are planning a road trip, you might also want to calculate the total driving time from Palatine, IL to Cape Girardeau, MO so you can see when you'll arrive at your destination.
You can also calculate the cost of driving from Palatine, IL to Cape Girardeau, MO based on current local fuel prices and an estimate of your car's best gas mileage.
If you're meeting a friend, you might be interested in finding the city that is halfway between Palatine, IL and Cape Girardeau, MO.
Planning to fly a plane instead? You might be more interested in calculating the straight line distance to fly from Palatine, IL to Cape Girardeau, MO.
Travelmath helps you find driving distances based on actual directions for your road trip. You can get the distance between cities, airports, states, countries, or zip codes to figure out the best route to travel to your destination. Combine this information with the fuel cost tool to find out how much it will cost you to drive the distance, or compare the results to the straight line distance to determine whether it's better to drive or fly. You can print out pages with a travel map.