Your total trip with all stops is around 1,210 miles / 1950 km, taking roughly 18.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Amarillo, TX and Appleton, WI.
Start from Amarillo, Texas.
Oklahoma City, Oklahoma is stopping point #1 after driving about 260 miles (420 km) or 4 hours.
Kansas City, Missouri is stopping point #2 after driving about 350 miles (570 km) or 5 hours. Your total trip so far is about 610 miles or 990 km over roughly 9 hours of driving.
Des Moines, Iowa is stopping point #3 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 810 miles or 1300 km over roughly 12 hours of driving.
Finally, Appleton, Wisconsin is your destination after driving about 400 miles (650 km) or 7 hours. Your total trip with all stops is around 1,210 miles or 1950 km, taking roughly 18.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.