Your total trip with all stops is around 1,470 miles / 2360 km, taking roughly 23 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Andover, MN and Hilton Head Island, SC.
Start from Andover, Minnesota.
Milwaukee, Wisconsin is stopping point #1 after driving about 350 miles (570 km) or 6 hours.
Lexington-Fayette, Kentucky is stopping point #2 after driving about 470 miles (750 km) or 7 hours. Your total trip so far is about 820 miles or 1320 km over roughly 13 hours of driving.
Charlotte, North Carolina is stopping point #3 after driving about 400 miles (640 km) or 6.5 hours. Your total trip so far is about 1,220 miles or 1970 km over roughly 19 hours of driving.
Finally, Hilton Head Island, South Carolina is your destination after driving about 250 miles (400 km) or 4 hours. Your total trip with all stops is around 1,470 miles or 2360 km, taking roughly 23 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.