Your total trip with all stops is around 830 miles / 1340 km, taking roughly 13.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between BWI and STL.
Start from Baltimore/Washington International Thurgood Marshall Airport.
Wheeling, West Virginia is stopping point #1 after driving about 280 miles (450 km) or 4.5 hours.
Columbus, Ohio is stopping point #2 after driving about 130 miles (200 km) or 2 hours. Your total trip so far is about 410 miles or 650 km over roughly 6.5 hours of driving.
Indianapolis, Indiana is stopping point #3 after driving about 180 miles (280 km) or 3 hours. Your total trip so far is about 580 miles or 940 km over roughly 9.5 hours of driving.
Finally, Lambert-St. Louis International Airport is your destination after driving about 250 miles (400 km) or 4 hours. Your total trip with all stops is around 830 miles or 1340 km, taking roughly 13.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.