Your total trip with all stops is around 1,470 miles / 2360 km, taking roughly 22 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Biloxi, MS and Cheyenne, WY.
Start from Biloxi, Mississippi.
Dallas, Texas is stopping point #1 after driving about 570 miles (920 km) or 8.5 hours.
Amarillo, Texas is stopping point #2 after driving about 360 miles (590 km) or 5.5 hours. Your total trip so far is about 940 miles or 1510 km over roughly 14 hours of driving.
Colorado Springs, Colorado is stopping point #3 after driving about 360 miles (580 km) or 5.5 hours. Your total trip so far is about 1,300 miles or 2090 km over roughly 19.5 hours of driving.
Finally, Cheyenne, Wyoming is your destination after driving about 170 miles (270 km) or 2.5 hours. Your total trip with all stops is around 1,470 miles or 2360 km, taking roughly 22 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.