Your total trip with all stops is around 970 miles / 1560 km, taking roughly 15 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between DCA and COU.
Start from Ronald Reagan Washington National Airport.
Wheeling, West Virginia is stopping point #1 after driving about 290 miles (470 km) or 4.5 hours.
Columbus, Ohio is stopping point #2 after driving about 130 miles (200 km) or 2 hours. Your total trip so far is about 420 miles or 680 km over roughly 6.5 hours of driving.
Indianapolis, Indiana is stopping point #3 after driving about 180 miles (280 km) or 2.5 hours. Your total trip so far is about 600 miles or 960 km over roughly 9 hours of driving.
Saint Louis, Missouri is stopping point #4 after driving about 240 miles (390 km) or 3.5 hours. Your total trip so far is about 840 miles or 1350 km over roughly 13 hours of driving.
Finally, Columbia Regional Airport is your destination after driving about 130 miles (220 km) or 2 hours. Your total trip with all stops is around 970 miles or 1560 km, taking roughly 15 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.