Stopping points from Des Moines International Airport to Gulfport-Biloxi International Airport:

• Start from Des Moines International Airport
• 4 hours to Columbia, Missouri after driving about 230 miles / 360 km
• 2 hours to Saint Louis, Missouri after driving about 130 miles / 200 km
• 4 hours to Memphis, Tennessee after driving about 280 miles / 460 km
• 3.5 hours to Brandon, Mississippi after driving about 220 miles / 360 km
• 3 hours to Gulfport-Biloxi International Airport after driving about 160 miles / 250 km

Your total trip with all stops is around 1,010 miles / 1630 km, taking roughly 16.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between DSM and GPT.

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Stopping points from DSM to GPT

Start from Des Moines International Airport.

Columbia, Missouri is stopping point #1 after driving about 230 miles (360 km) or 4 hours.

Saint Louis, Missouri is stopping point #2 after driving about 130 miles (200 km) or 2 hours. Your total trip so far is about 350 miles or 560 km over roughly 6 hours of driving.

Memphis, Tennessee is stopping point #3 after driving about 280 miles (460 km) or 4 hours. Your total trip so far is about 630 miles or 1020 km over roughly 10 hours of driving.

Brandon, Mississippi is stopping point #4 after driving about 220 miles (360 km) or 3.5 hours. Your total trip so far is about 860 miles or 1380 km over roughly 13.5 hours of driving.

Finally, Gulfport-Biloxi International Airport is your destination after driving about 160 miles (250 km) or 3 hours. Your total trip with all stops is around 1,010 miles or 1630 km, taking roughly 16.5 hours for the whole trip.

Stopping point calculator

Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.