Your total trip with all stops is around 1,190 miles / 1910 km, taking roughly 18 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between DTW and TPA.
Start from Detroit Metropolitan Wayne County Airport.
Cincinnati, Ohio is stopping point #1 after driving about 240 miles (390 km) or 3.5 hours.
Knoxville, Tennessee is stopping point #2 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 500 miles or 810 km over roughly 8 hours of driving.
Atlanta, Georgia is stopping point #3 after driving about 210 miles (340 km) or 3 hours. Your total trip so far is about 720 miles or 1150 km over roughly 11 hours of driving.
Gainesville, Florida is stopping point #4 after driving about 330 miles (530 km) or 4.5 hours. Your total trip so far is about 1,050 miles or 1690 km over roughly 15.5 hours of driving.
Finally, Tampa International Airport is your destination after driving about 140 miles (220 km) or 2.5 hours. Your total trip with all stops is around 1,190 miles or 1910 km, taking roughly 18 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.