Your total trip with all stops is around 1,500 miles / 2420 km, taking roughly 23.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Del Rio, TX and Appleton, WI.
Start from Del Rio, Texas.
Abilene, Texas is stopping point #1 after driving about 250 miles (400 km) or 4 hours.
Oklahoma City, Oklahoma is stopping point #2 after driving about 290 miles (470 km) or 4.5 hours. Your total trip so far is about 540 miles or 870 km over roughly 8.5 hours of driving.
Saint Louis, Missouri is stopping point #3 after driving about 500 miles (800 km) or 7.5 hours. Your total trip so far is about 1,040 miles or 1670 km over roughly 16 hours of driving.
Rockford, Illinois is stopping point #4 after driving about 300 miles (470 km) or 4.5 hours. Your total trip so far is about 1,330 miles or 2150 km over roughly 20 hours of driving.
Finally, Appleton, Wisconsin is your destination after driving about 170 miles (270 km) or 3 hours. Your total trip with all stops is around 1,500 miles or 2420 km, taking roughly 23.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.