Your total trip with all stops is around 720 miles / 1160 km, taking roughly 11 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between EWR and GSP.
Start from Newark Liberty International Airport.
Baltimore, Maryland is stopping point #1 after driving about 180 miles (290 km) or 3 hours.
Richmond, Virginia is stopping point #2 after driving about 150 miles (250 km) or 2.5 hours. Your total trip so far is about 330 miles or 540 km over roughly 5.5 hours of driving.
Charlotte, North Carolina is stopping point #3 after driving about 300 miles (470 km) or 4.5 hours. Your total trip so far is about 630 miles or 1010 km over roughly 9.5 hours of driving.
Finally, Greenville-Spartanburg International Airport is your destination after driving about 90 miles (140 km) or 1.5 hours. Your total trip with all stops is around 720 miles or 1160 km, taking roughly 11 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.