Your total trip with all stops is around 1,370 miles / 2200 km, taking roughly 21 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between EWR and MSY.
Start from Newark Liberty International Airport.
Richmond, Virginia is stopping point #1 after driving about 320 miles (520 km) or 5.5 hours.
Knoxville, Tennessee is stopping point #2 after driving about 430 miles (700 km) or 6.5 hours. Your total trip so far is about 750 miles or 1210 km over roughly 11.5 hours of driving.
Birmingham, Alabama is stopping point #3 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 1,010 miles or 1630 km over roughly 15.5 hours of driving.
Finally, Louis Armstrong New Orleans International Airport is your destination after driving about 360 miles (570 km) or 5.5 hours. Your total trip with all stops is around 1,370 miles or 2200 km, taking roughly 21 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.