Your total trip with all stops is around 910 miles / 1460 km, taking roughly 14.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Eau Claire, WI and Cheyenne, WY.
Start from Eau Claire, Wisconsin.
Sioux Falls, South Dakota is stopping point #1 after driving about 320 miles (520 km) or 5 hours.
Scottsbluff, Nebraska is stopping point #2 after driving about 490 miles (780 km) or 7.5 hours. Your total trip so far is about 810 miles or 1300 km over roughly 12.5 hours of driving.
Finally, Cheyenne, Wyoming is your destination after driving about 100 miles (160 km) or 1.5 hours. Your total trip with all stops is around 910 miles or 1460 km, taking roughly 14.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.