Stopping points from Florence, South Carolina to Chicago, Illinois:

• Start from Florence, South Carolina
• 4 hours to Asheville, North Carolina after driving about 240 miles / 380 km
• 4.5 hours to Lexington-Fayette, Kentucky after driving about 280 miles / 460 km
• 3 hours to Indianapolis, Indiana after driving about 190 miles / 310 km
• 3 hours to Chicago, Illinois after driving about 180 miles / 290 km

Your total trip with all stops is around 890 miles / 1430 km, taking roughly 14.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Florence, SC and Chicago, IL.

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Stopping points from Florence, SC to Chicago, IL

Start from Florence, South Carolina.

Asheville, North Carolina is stopping point #1 after driving about 240 miles (380 km) or 4 hours.

Lexington-Fayette, Kentucky is stopping point #2 after driving about 280 miles (460 km) or 4.5 hours. Your total trip so far is about 520 miles or 830 km over roughly 8.5 hours of driving.

Indianapolis, Indiana is stopping point #3 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 710 miles or 1140 km over roughly 11.5 hours of driving.

Finally, Chicago, Illinois is your destination after driving about 180 miles (290 km) or 3 hours. Your total trip with all stops is around 890 miles or 1430 km, taking roughly 14.5 hours for the whole trip.

Stopping point calculator

Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.