Your total trip with all stops is around 1,410 miles / 2260 km, taking roughly 22 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Framingham, MA and Springfield, MO.
Start from Framingham, Massachusetts.
Rochester, New York is stopping point #1 after driving about 370 miles (600 km) or 6 hours.
Cleveland, Ohio is stopping point #2 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 630 miles or 1020 km over roughly 10 hours of driving.
Indianapolis, Indiana is stopping point #3 after driving about 320 miles (510 km) or 5 hours. Your total trip so far is about 950 miles or 1520 km over roughly 15 hours of driving.
Saint Louis, Missouri is stopping point #4 after driving about 240 miles (390 km) or 3.5 hours. Your total trip so far is about 1,190 miles or 1910 km over roughly 18.5 hours of driving.
Finally, Springfield, Missouri is your destination after driving about 220 miles (350 km) or 3.5 hours. Your total trip with all stops is around 1,410 miles or 2260 km, taking roughly 22 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.