Your total trip with all stops is around 570 miles / 910 km, taking roughly 9 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between GPT and TPA.
Start from Gulfport-Biloxi International Airport.
Pensacola, Florida is stopping point #1 after driving about 130 miles (210 km) or 2 hours.
Tallahassee, Florida is stopping point #2 after driving about 200 miles (320 km) or 3 hours. Your total trip so far is about 330 miles or 520 km over roughly 5 hours of driving.
Finally, Tampa International Airport is your destination after driving about 240 miles (380 km) or 4 hours. Your total trip with all stops is around 570 miles or 910 km, taking roughly 9 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.