Your total trip with all stops is around 1,680 miles / 2710 km, taking roughly 25.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between GSO and CYS.
Start from Piedmont Triad International Airport.
Lexington-Fayette, Kentucky is stopping point #1 after driving about 410 miles (660 km) or 6.5 hours.
Saint Louis, Missouri is stopping point #2 after driving about 340 miles (540 km) or 5.5 hours. Your total trip so far is about 750 miles or 1210 km over roughly 12 hours of driving.
Kansas City, Missouri is stopping point #3 after driving about 250 miles (400 km) or 3.5 hours. Your total trip so far is about 1,000 miles or 1600 km over roughly 15.5 hours of driving.
Omaha, Nebraska is stopping point #4 after driving about 190 miles (300 km) or 3 hours. Your total trip so far is about 1,180 miles or 1900 km over roughly 18.5 hours of driving.
Finally, Cheyenne Regional Airport is your destination after driving about 500 miles (800 km) or 7 hours. Your total trip with all stops is around 1,680 miles or 2710 km, taking roughly 25.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.