Your total trip with all stops is around 950 miles / 1520 km, taking roughly 16 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Georgetown, SC and Chicago, IL.
Start from Georgetown, South Carolina.
Charlotte, North Carolina is stopping point #1 after driving about 170 miles (280 km) or 3.5 hours.
Knoxville, Tennessee is stopping point #2 after driving about 230 miles (370 km) or 4 hours. Your total trip so far is about 400 miles or 650 km over roughly 7.5 hours of driving.
Lexington-Fayette, Kentucky is stopping point #3 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 570 miles or 920 km over roughly 10 hours of driving.
Indianapolis, Indiana is stopping point #4 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 760 miles or 1230 km over roughly 13 hours of driving.
Finally, Chicago, Illinois is your destination after driving about 180 miles (290 km) or 3 hours. Your total trip with all stops is around 950 miles or 1520 km, taking roughly 16 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.