Your total trip with all stops is around 2,550 miles / 4100 km, taking roughly 41.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Guadalajara, Mexico and Reading, PA.
Start from Guadalajara, Mexico.
Saltillo, Mexico is stopping point #1 after driving about 500 miles (810 km) or 10 hours.
Houston, Texas is stopping point #2 after driving about 510 miles (810 km) or 8.5 hours. Your total trip so far is about 1,010 miles or 1630 km over roughly 18 hours of driving.
Baton Rouge, Louisiana is stopping point #3 after driving about 270 miles (440 km) or 4 hours. Your total trip so far is about 1,280 miles or 2060 km over roughly 22.5 hours of driving.
Birmingham, Alabama is stopping point #4 after driving about 400 miles (640 km) or 6 hours. Your total trip so far is about 1,680 miles or 2700 km over roughly 28 hours of driving.
Knoxville, Tennessee is stopping point #5 after driving about 260 miles (410 km) or 3.5 hours. Your total trip so far is about 1,940 miles or 3120 km over roughly 32 hours of driving.
Roanoke, Virginia is stopping point #6 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 2,200 miles or 3530 km over roughly 36 hours of driving.
Finally, Reading, Pennsylvania is your destination after driving about 350 miles (570 km) or 6 hours. Your total trip with all stops is around 2,550 miles or 4100 km, taking roughly 41.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.