Your total trip with all stops is around 670 miles / 1070 km, taking roughly 12.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Guerrero Negro, Mexico and Tucson, AZ.
Start from Guerrero Negro, Mexico.
San Felipe, Mexico is stopping point #1 after driving about 250 miles (400 km) or 5.5 hours.
San Luis Rio Colorado, Mexico is stopping point #2 after driving about 160 miles (250 km) or 3 hours. Your total trip so far is about 410 miles or 660 km over roughly 8.5 hours of driving.
Finally, Tucson, Arizona is your destination after driving about 260 miles (420 km) or 4 hours. Your total trip with all stops is around 670 miles or 1070 km, taking roughly 12.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.