Your total trip with all stops is around 1,960 miles / 3150 km, taking roughly 29.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between IAH and SFO.
Start from George Bush Intercontinental Airport.
San Antonio, Texas is stopping point #1 after driving about 210 miles (340 km) or 3.5 hours.
Juarez, Mexico is stopping point #2 after driving about 550 miles (890 km) or 8 hours. Your total trip so far is about 770 miles or 1230 km over roughly 11 hours of driving.
Tucson, Arizona is stopping point #3 after driving about 320 miles (510 km) or 5 hours. Your total trip so far is about 1,080 miles or 1740 km over roughly 16 hours of driving.
Los Angeles, California is stopping point #4 after driving about 490 miles (790 km) or 7.5 hours. Your total trip so far is about 1,570 miles or 2530 km over roughly 23.5 hours of driving.
Finally, San Francisco International Airport is your destination after driving about 380 miles (620 km) or 6 hours. Your total trip with all stops is around 1,960 miles or 3150 km, taking roughly 29.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.