Your total trip with all stops is around 960 miles / 1540 km, taking roughly 16 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Lexington, MA and Indianapolis, IN.
Start from Lexington, Massachusetts.
New Haven, Connecticut is stopping point #1 after driving about 140 miles (220 km) or 2 hours.
Scranton, Pennsylvania is stopping point #2 after driving about 170 miles (270 km) or 3 hours. Your total trip so far is about 310 miles or 490 km over roughly 5.5 hours of driving.
Akron, Ohio is stopping point #3 after driving about 350 miles (560 km) or 6 hours. Your total trip so far is about 660 miles or 1060 km over roughly 11 hours of driving.
Columbus, Ohio is stopping point #4 after driving about 130 miles (200 km) or 2 hours. Your total trip so far is about 780 miles or 1260 km over roughly 13 hours of driving.
Finally, Indianapolis, Indiana is your destination after driving about 180 miles (280 km) or 3 hours. Your total trip with all stops is around 960 miles or 1540 km, taking roughly 16 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.