Your total trip with all stops is around 1,460 miles / 2350 km, taking roughly 24 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between MCO and DTW.
Start from Orlando International Airport.
Gainesville, Florida is stopping point #1 after driving about 120 miles (200 km) or 2 hours.
Atlanta, Georgia is stopping point #2 after driving about 340 miles (540 km) or 5.5 hours. Your total trip so far is about 460 miles or 740 km over roughly 7.5 hours of driving.
Knoxville, Tennessee is stopping point #3 after driving about 200 miles (330 km) or 3.5 hours. Your total trip so far is about 660 miles or 1060 km over roughly 11 hours of driving.
Lexington-Fayette, Kentucky is stopping point #4 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 830 miles or 1340 km over roughly 13.5 hours of driving.
Finally, Detroit Metropolitan Wayne County Airport is your destination after driving about 630 miles (1020 km) or 10.5 hours. Your total trip with all stops is around 1,460 miles or 2350 km, taking roughly 24 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.