Stopping points from Minneapolis-Saint Paul International Airport to Greenville-Spartanburg International Airport:

• Start from Minneapolis-Saint Paul International Airport
• 4.5 hours to Madison, Wisconsin after driving about 270 miles / 440 km
• 2.5 hours to Chicago, Illinois after driving about 150 miles / 240 km
• 3 hours to Indianapolis, Indiana after driving about 180 miles / 290 km
• 3 hours to Lexington-Fayette, Kentucky after driving about 190 miles / 310 km
• 2.5 hours to Knoxville, Tennessee after driving about 170 miles / 270 km
• 3 hours to Greenville-Spartanburg International Airport after driving about 180 miles / 290 km

Your total trip with all stops is around 1,140 miles / 1840 km, taking roughly 19 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between MSP and GSP.

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Stopping points from MSP to GSP

Start from Minneapolis-Saint Paul International Airport.

Madison, Wisconsin is stopping point #1 after driving about 270 miles (440 km) or 4.5 hours.

Chicago, Illinois is stopping point #2 after driving about 150 miles (240 km) or 2.5 hours. Your total trip so far is about 420 miles or 670 km over roughly 7.5 hours of driving.

Indianapolis, Indiana is stopping point #3 after driving about 180 miles (290 km) or 3 hours. Your total trip so far is about 600 miles or 960 km over roughly 10.5 hours of driving.

Lexington-Fayette, Kentucky is stopping point #4 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 790 miles or 1270 km over roughly 13.5 hours of driving.

Knoxville, Tennessee is stopping point #5 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 960 miles or 1540 km over roughly 16 hours of driving.

Finally, Greenville-Spartanburg International Airport is your destination after driving about 180 miles (290 km) or 3 hours. Your total trip with all stops is around 1,140 miles or 1840 km, taking roughly 19 hours for the whole trip.

Stopping point calculator

Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.