Your total trip with all stops is around 1,460 miles / 2340 km, taking roughly 22 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between MSP and HHH.
Start from Minneapolis-Saint Paul International Airport.
Milwaukee, Wisconsin is stopping point #1 after driving about 340 miles (540 km) or 5 hours.
Lexington-Fayette, Kentucky is stopping point #2 after driving about 470 miles (750 km) or 7 hours. Your total trip so far is about 810 miles or 1300 km over roughly 12 hours of driving.
Charlotte, North Carolina is stopping point #3 after driving about 400 miles (640 km) or 6.5 hours. Your total trip so far is about 1,210 miles or 1940 km over roughly 18 hours of driving.
Finally, Hilton Head Airport is your destination after driving about 250 miles (400 km) or 4 hours. Your total trip with all stops is around 1,460 miles or 2340 km, taking roughly 22 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.