Your total trip with all stops is around 1,590 miles / 2560 km, taking roughly 23.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Mesa, AZ and Biloxi, MS.
Start from Mesa, Arizona.
El Paso, Texas is stopping point #1 after driving about 430 miles (700 km) or 6 hours.
Austin, Texas is stopping point #2 after driving about 580 miles (930 km) or 8.5 hours. Your total trip so far is about 1,010 miles or 1620 km over roughly 15 hours of driving.
Houston, Texas is stopping point #3 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 1,170 miles or 1890 km over roughly 17.5 hours of driving.
Finally, Biloxi, Mississippi is your destination after driving about 410 miles (670 km) or 6 hours. Your total trip with all stops is around 1,590 miles or 2560 km, taking roughly 23.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.