Stopping points from Missouri (MO) to Indiana (IN):

• Start from Missouri (MO)
• 2.5 hours to Saint Louis, Missouri after driving about 140 miles / 230 km
• 4 hours to Indiana (IN) after driving about 250 miles / 400 km

Your total trip with all stops is around 390 miles / 630 km, taking roughly 6 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Missouri and Indiana.

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Stopping points from Missouri to Indiana

Start from Missouri (MO).

Saint Louis, Missouri is stopping point #1 after driving about 140 miles (230 km) or 2.5 hours.

Finally, Indiana (IN) is your destination after driving about 250 miles (400 km) or 4 hours. Your total trip with all stops is around 390 miles or 630 km, taking roughly 6 hours for the whole trip.

Stopping point calculator

Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.