Your total trip with all stops is around 4,030 miles / 6490 km, taking roughly 75.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between New Berlin, WI and Panama City, Panama.
Start from New Berlin, Wisconsin.
Saint Louis, Missouri is stopping point #1 after driving about 370 miles (590 km) or 5.5 hours.
Shreveport, Louisiana is stopping point #2 after driving about 560 miles (890 km) or 8.5 hours. Your total trip so far is about 920 miles or 1490 km over roughly 14 hours of driving.
Houston, Texas is stopping point #3 after driving about 240 miles (380 km) or 4 hours. Your total trip so far is about 1,160 miles or 1870 km over roughly 18 hours of driving.
Tampico, Mexico is stopping point #4 after driving about 660 miles (1060 km) or 11.5 hours. Your total trip so far is about 1,820 miles or 2930 km over roughly 29 hours of driving.
Veracruz, Mexico is stopping point #5 after driving about 300 miles (470 km) or 7.5 hours. Your total trip so far is about 2,120 miles or 3400 km over roughly 36.5 hours of driving.
Choloma, Honduras is stopping point #6 after driving about 710 miles (1150 km) or 12 hours. Your total trip so far is about 2,830 miles or 4550 km over roughly 48.5 hours of driving.
Managua, Nicaragua is stopping point #7 after driving about 410 miles (660 km) or 8.5 hours. Your total trip so far is about 3,230 miles or 5210 km over roughly 57 hours of driving.
San Jose, Costa Rica is stopping point #8 after driving about 270 miles (430 km) or 6.5 hours. Your total trip so far is about 3,500 miles or 5630 km over roughly 64 hours of driving.
Finally, Panama City, Panama is your destination after driving about 530 miles (850 km) or 11.5 hours. Your total trip with all stops is around 4,030 miles or 6490 km, taking roughly 75.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.