Your total trip with all stops is around 1,280 miles / 2060 km, taking roughly 19.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between New Mexico and Indiana.
Start from New Mexico (NM).
Amarillo, Texas is stopping point #1 after driving about 270 miles (440 km) or 4.5 hours.
Oklahoma City, Oklahoma is stopping point #2 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 530 miles or 850 km over roughly 8 hours of driving.
Saint Louis, Missouri is stopping point #3 after driving about 500 miles (800 km) or 7.5 hours. Your total trip so far is about 1,030 miles or 1660 km over roughly 15.5 hours of driving.
Finally, Indiana (IN) is your destination after driving about 250 miles (400 km) or 4 hours. Your total trip with all stops is around 1,280 miles or 2060 km, taking roughly 19.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.