Stopping points from Chicago O'Hare International Airport to Greenville-Spartanburg International Airport:

• Start from Chicago O'Hare International Airport
• 3 hours to Indianapolis, Indiana after driving about 200 miles / 330 km
• 3 hours to Lexington-Fayette, Kentucky after driving about 190 miles / 310 km
• 2.5 hours to Knoxville, Tennessee after driving about 170 miles / 270 km
• 3 hours to Greenville-Spartanburg International Airport after driving about 180 miles / 290 km

Your total trip with all stops is around 750 miles / 1200 km, taking roughly 12 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between ORD and GSP.

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Stopping points from ORD to GSP

Start from Chicago O'Hare International Airport.

Indianapolis, Indiana is stopping point #1 after driving about 200 miles (330 km) or 3 hours.

Lexington-Fayette, Kentucky is stopping point #2 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 390 miles or 630 km over roughly 6 hours of driving.

Knoxville, Tennessee is stopping point #3 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 560 miles or 910 km over roughly 8.5 hours of driving.

Finally, Greenville-Spartanburg International Airport is your destination after driving about 180 miles (290 km) or 3 hours. Your total trip with all stops is around 750 miles or 1200 km, taking roughly 12 hours for the whole trip.

Stopping point calculator

Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.