Your total trip with all stops is around 810 miles / 1300 km, taking roughly 13 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Ohio and Mississippi.
Start from Ohio (OH).
Cincinnati, Ohio is stopping point #1 after driving about 140 miles (220 km) or 2.5 hours.
Nashville, Tennessee is stopping point #2 after driving about 280 miles (450 km) or 4.5 hours. Your total trip so far is about 420 miles or 670 km over roughly 6.5 hours of driving.
Jackson, Tennessee is stopping point #3 after driving about 130 miles (210 km) or 2 hours. Your total trip so far is about 550 miles or 880 km over roughly 9 hours of driving.
Finally, Mississippi (MS) is your destination after driving about 260 miles (420 km) or 4.5 hours. Your total trip with all stops is around 810 miles or 1300 km, taking roughly 13 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.