Your total trip with all stops is around 910 miles / 1460 km, taking roughly 14 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Plainfield, IL and Florence, SC.
Start from Plainfield, Illinois.
Indianapolis, Indiana is stopping point #1 after driving about 200 miles (320 km) or 3 hours.
Lexington-Fayette, Kentucky is stopping point #2 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 390 miles or 630 km over roughly 6 hours of driving.
Knoxville, Tennessee is stopping point #3 after driving about 170 miles (270 km) or 2.5 hours. Your total trip so far is about 560 miles or 900 km over roughly 8.5 hours of driving.
Columbia, South Carolina is stopping point #4 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 820 miles or 1320 km over roughly 12.5 hours of driving.
Finally, Florence, South Carolina is your destination after driving about 80 miles (130 km) or 1.5 hours. Your total trip with all stops is around 910 miles or 1460 km, taking roughly 14 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.