Your total trip with all stops is around 1,010 miles / 1620 km, taking roughly 16 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Portland, ME and Florence, SC.
Start from Portland, Maine.
Providence, Rhode Island is stopping point #1 after driving about 160 miles (260 km) or 2.5 hours.
New York, New York is stopping point #2 after driving about 180 miles (290 km) or 3 hours. Your total trip so far is about 340 miles or 550 km over roughly 6 hours of driving.
Baltimore, Maryland is stopping point #3 after driving about 190 miles (310 km) or 3 hours. Your total trip so far is about 540 miles or 860 km over roughly 9 hours of driving.
Raleigh, North Carolina is stopping point #4 after driving about 320 miles (520 km) or 5 hours. Your total trip so far is about 860 miles or 1380 km over roughly 14 hours of driving.
Finally, Florence, South Carolina is your destination after driving about 150 miles (240 km) or 2 hours. Your total trip with all stops is around 1,010 miles or 1620 km, taking roughly 16 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.