Your total trip with all stops is around 3,260 miles / 5240 km, taking roughly 48.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between RSW and LKE.
Start from Southwest Florida International Airport.
Gainesville, Florida is stopping point #1 after driving about 260 miles (420 km) or 4 hours.
Nashville, Tennessee is stopping point #2 after driving about 580 miles (940 km) or 8.5 hours. Your total trip so far is about 840 miles or 1360 km over roughly 12.5 hours of driving.
Saint Louis, Missouri is stopping point #3 after driving about 310 miles (500 km) or 4.5 hours. Your total trip so far is about 1,150 miles or 1850 km over roughly 17 hours of driving.
Kansas City, Missouri is stopping point #4 after driving about 250 miles (400 km) or 3.5 hours. Your total trip so far is about 1,400 miles or 2250 km over roughly 20.5 hours of driving.
Sioux Falls, South Dakota is stopping point #5 after driving about 360 miles (590 km) or 5.5 hours. Your total trip so far is about 1,760 miles or 2840 km over roughly 26 hours of driving.
Rapid City, South Dakota is stopping point #6 after driving about 350 miles (560 km) or 5 hours. Your total trip so far is about 2,110 miles or 3400 km over roughly 31 hours of driving.
Billings, Montana is stopping point #7 after driving about 320 miles (510 km) or 5 hours. Your total trip so far is about 2,430 miles or 3920 km over roughly 36 hours of driving.
Missoula, Montana is stopping point #8 after driving about 350 miles (560 km) or 5 hours. Your total trip so far is about 2,780 miles or 4470 km over roughly 41 hours of driving.
Finally, Kenmore Air Harbor Seaplane Base is your destination after driving about 480 miles (770 km) or 7.5 hours. Your total trip with all stops is around 3,260 miles or 5240 km, taking roughly 48.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.