Your total trip with all stops is around 1,550 miles / 2500 km, taking roughly 24.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Reading, PA and Houston, TX.
Start from Reading, Pennsylvania.
Roanoke, Virginia is stopping point #1 after driving about 350 miles (570 km) or 5.5 hours.
Knoxville, Tennessee is stopping point #2 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 610 miles or 990 km over roughly 10 hours of driving.
Birmingham, Alabama is stopping point #3 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 870 miles or 1400 km over roughly 14 hours of driving.
Baton Rouge, Louisiana is stopping point #4 after driving about 400 miles (640 km) or 6 hours. Your total trip so far is about 1,270 miles or 2040 km over roughly 20 hours of driving.
Finally, Houston, Texas is your destination after driving about 280 miles (460 km) or 4.5 hours. Your total trip with all stops is around 1,550 miles or 2500 km, taking roughly 24.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.