Your total trip with all stops is around 1,220 miles / 1970 km, taking roughly 18.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between STL and BOS.
Start from Lambert-St. Louis International Airport.
Indianapolis, Indiana is stopping point #1 after driving about 250 miles (400 km) or 4 hours.
Cleveland, Ohio is stopping point #2 after driving about 320 miles (510 km) or 5 hours. Your total trip so far is about 570 miles or 910 km over roughly 8.5 hours of driving.
Rochester, New York is stopping point #3 after driving about 260 miles (420 km) or 4 hours. Your total trip so far is about 830 miles or 1330 km over roughly 12.5 hours of driving.
Finally, Boston Logan International Airport is your destination after driving about 400 miles (640 km) or 6 hours. Your total trip with all stops is around 1,220 miles or 1970 km, taking roughly 18.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.