Your total trip with all stops is around 2,080 miles / 3340 km, taking roughly 31 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between STL and SFO.
Start from Lambert-St. Louis International Airport.
Kansas City, Missouri is stopping point #1 after driving about 240 miles (380 km) or 3.5 hours.
Grand Island, Nebraska is stopping point #2 after driving about 290 miles (470 km) or 4.5 hours. Your total trip so far is about 530 miles or 840 km over roughly 8.5 hours of driving.
Cheyenne, Wyoming is stopping point #3 after driving about 360 miles (580 km) or 5 hours. Your total trip so far is about 890 miles or 1430 km over roughly 13.5 hours of driving.
Salt Lake City, Utah is stopping point #4 after driving about 440 miles (710 km) or 6.5 hours. Your total trip so far is about 1,330 miles or 2140 km over roughly 20 hours of driving.
Reno, Nevada is stopping point #5 after driving about 520 miles (840 km) or 7.5 hours. Your total trip so far is about 1,850 miles or 2970 km over roughly 27 hours of driving.
Finally, San Francisco International Airport is your destination after driving about 230 miles (370 km) or 4 hours. Your total trip with all stops is around 2,080 miles or 3340 km, taking roughly 31 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.