Your total trip with all stops is around 1,350 miles / 2170 km, taking roughly 21 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Scranton, PA and Biloxi, MS.
Start from Scranton, Pennsylvania.
Richmond, Virginia is stopping point #1 after driving about 340 miles (550 km) or 5.5 hours.
Knoxville, Tennessee is stopping point #2 after driving about 430 miles (700 km) or 6.5 hours. Your total trip so far is about 770 miles or 1250 km over roughly 12 hours of driving.
Birmingham, Alabama is stopping point #3 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 1,030 miles or 1660 km over roughly 16 hours of driving.
Finally, Biloxi, Mississippi is your destination after driving about 320 miles (510 km) or 5 hours. Your total trip with all stops is around 1,350 miles or 2170 km, taking roughly 21 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.