Your total trip with all stops is around 1,040 miles / 1670 km, taking roughly 17 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Springfield, IL and Charleston, SC.
Start from Springfield, Illinois.
Cape Girardeau, Missouri is stopping point #1 after driving about 220 miles (350 km) or 3.5 hours.
Nashville, Tennessee is stopping point #2 after driving about 200 miles (330 km) or 3.5 hours. Your total trip so far is about 420 miles or 670 km over roughly 7 hours of driving.
Knoxville, Tennessee is stopping point #3 after driving about 180 miles (290 km) or 3 hours. Your total trip so far is about 600 miles or 970 km over roughly 10 hours of driving.
Charlotte, North Carolina is stopping point #4 after driving about 230 miles (370 km) or 3.5 hours. Your total trip so far is about 830 miles or 1340 km over roughly 13.5 hours of driving.
Finally, Charleston, South Carolina is your destination after driving about 210 miles (340 km) or 3.5 hours. Your total trip with all stops is around 1,040 miles or 1670 km, taking roughly 17 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.