Your total trip with all stops is around 1,030 miles / 1660 km, taking roughly 16 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between Springfield, MO and Rochester, NY.
Start from Springfield, Missouri.
Saint Louis, Missouri is stopping point #1 after driving about 220 miles (350 km) or 3 hours.
Indianapolis, Indiana is stopping point #2 after driving about 240 miles (390 km) or 4 hours. Your total trip so far is about 460 miles or 740 km over roughly 7 hours of driving.
Columbus, Ohio is stopping point #3 after driving about 180 miles (280 km) or 2.5 hours. Your total trip so far is about 630 miles or 1020 km over roughly 10 hours of driving.
Cleveland, Ohio is stopping point #4 after driving about 140 miles (230 km) or 2.5 hours. Your total trip so far is about 780 miles or 1250 km over roughly 12.5 hours of driving.
Finally, Rochester, New York is your destination after driving about 260 miles (420 km) or 4 hours. Your total trip with all stops is around 1,030 miles or 1660 km, taking roughly 16 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.