Your total trip with all stops is around 960 miles / 1540 km, taking roughly 15 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between State College, PA and Springfield, MO.
Start from State College, Pennsylvania.
Pittsburgh, Pennsylvania is stopping point #1 after driving about 140 miles (230 km) or 2.5 hours.
Columbus, Ohio is stopping point #2 after driving about 190 miles (300 km) or 3 hours. Your total trip so far is about 330 miles or 520 km over roughly 5.5 hours of driving.
Indianapolis, Indiana is stopping point #3 after driving about 180 miles (280 km) or 2.5 hours. Your total trip so far is about 500 miles or 810 km over roughly 8 hours of driving.
Saint Louis, Missouri is stopping point #4 after driving about 240 miles (390 km) or 3.5 hours. Your total trip so far is about 740 miles or 1200 km over roughly 12 hours of driving.
Finally, Springfield, Missouri is your destination after driving about 220 miles (350 km) or 3.5 hours. Your total trip with all stops is around 960 miles or 1540 km, taking roughly 15 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.