Your total trip with all stops is around 970 miles / 1570 km, taking roughly 15.5 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between TPA and IAH.
Start from Tampa International Airport.
Tallahassee, Florida is stopping point #1 after driving about 240 miles (390 km) or 4 hours.
Pensacola, Florida is stopping point #2 after driving about 200 miles (320 km) or 3 hours. Your total trip so far is about 440 miles or 700 km over roughly 7 hours of driving.
Baton Rouge, Louisiana is stopping point #3 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 690 miles or 1120 km over roughly 11 hours of driving.
Finally, George Bush Intercontinental Airport is your destination after driving about 280 miles (450 km) or 4.5 hours. Your total trip with all stops is around 970 miles or 1570 km, taking roughly 15.5 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.