Your total trip with all stops is around 1,170 miles / 1870 km, taking roughly 18 hours for the whole trip. If you want to see every small town along the way, you can get a full list of cities between TPA and SAT.
Start from Tampa International Airport.
Tallahassee, Florida is stopping point #1 after driving about 240 miles (390 km) or 4 hours.
Pensacola, Florida is stopping point #2 after driving about 200 miles (320 km) or 3 hours. Your total trip so far is about 440 miles or 700 km over roughly 7 hours of driving.
Baton Rouge, Louisiana is stopping point #3 after driving about 260 miles (410 km) or 4 hours. Your total trip so far is about 690 miles or 1120 km over roughly 11 hours of driving.
Houston, Texas is stopping point #4 after driving about 270 miles (440 km) or 4 hours. Your total trip so far is about 960 miles or 1550 km over roughly 15 hours of driving.
Finally, San Antonio International Airport is your destination after driving about 200 miles (320 km) or 3 hours. Your total trip with all stops is around 1,170 miles or 1870 km, taking roughly 18 hours for the whole trip.
Travelmath helps you figure out where to stop when planning a long road trip from one location to another. The best stopping point for an overnight hotel stay or a break from driving often depends on how far or how long you want to drive before pausing to rest. You can find the closest city to your stopping point to look for hotels, or explore other cities and towns along the route. Use this as a road trip planner when you're driving cross-country or mapping a route with multiple stops.